Herf&Turf is correct about that not being their building. The sign is still there but not on that building. It is in front of a newer shop on 7th.I think Tony's thinking of the Tampa Sweethearts building, which IIRC was indeed built as a cigar factory in 1895 and purchased by Arturo Fuente in 1912.
However, the building in the pic isn't that building. The building in the pic is actually in downtown Ybor and wasn't a Fuente building. It still bears that old sign, but to my knowledge, the building never belonged to Fuente. My best guess is that the building dates to the early teens and the sign dates back to the 1950's.